Pulmonary Uptake of MDP

PULMONARY UPTAKE OF MDP Radionuclide bone scanning is now a standard technique in the staging of many malignancies. Probably the most frequent application is in screening patients with known primary malignancy and potential bone metastases. In primary malignant bone tumours, bone scanning is also useful with images often showing the lesion to be more extensive than was suspected from radiographs (McKillop et al., 1974). Bone forming metastases in the lungs can sometimes be detected before they become visible on the chest radiograph (McKillop et al. 1974, Robinson 1979, Ghaed et al. 1981). Although radionuclide imaging of bone is very sensitive, it is of low specificity and a variety of other pathologies can also be shown. It is occasionally difficult when looking at the thorax on the bone